Pictures of asthma
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Researchers at Duke University Medical Center appear to have solved at least a piece of a puzzle that has mystified physicians for years: why so many patients with asthma also suffer from GERD, or gastroesophageal reflux disease.
Clinicians first noted a relationship between the two diseases in the mid-1970s. Since then, studies have shown that anywhere from 50 to 90 percent of patients with asthma experience some aspect of GERD. But can GERD cause asthma, or, is it the other way around? Perhaps there is some shared mechanism at the root of both disorders causing them to arise together. Physicians could make a case for each scenario, but until now, the exact nature of the relationship was not clear.
Working in laboratory experiments with mice, Dr
The findings indicated that early life exposure to the chemicals contained in household cleaning products was linked to a 41% increase in a child s chances of developing asthma by the age of 7 years. During the study, a large number of other factors known to affect the onset of asthma, such as family history, were accounted for.
The results thus present a possible mechanism for the hygiene hypothesis , which suggests that children brought up with low exposure to bacteria and dust in the home in their early years are less likely to build an immunity to asthma later in life.
Dr. Alexandra Farrow, Reader at Brunel University s School of Health Sciences and Social Care and a member of the ALSPAC research team, explains: Previous research has shown that a child s risk of developing asthma is lower if he or she is exposed to bacteria or bacterial products (endotoxins) in early life ( hygiene hypothesis ), probably because it assists in the development of a child s immune system.
However, our research suggests that one possible mechanism for this hypothesis may involve the chemicals found in domestic cleaning products. These chemicals have been linked to increased risk of asthma with additional evidence from studies of workers who have exposure to cleaning chemicals
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